The McArthur lab is proud to collaborate with colleagues in the Faculty of Science on the metabolic and transcriptional responses to human inactivity and aging under the leadership of Dr. Stuart Phillips (pictured) of the Department of Kinesiology’s Exercise Metabolism Research Group. Dr. Phillips successfully competed in Faculty of Science Call for Interdisciplinary Projects 2015 to obtain funding for this project, which also includes Dr. Martin Gibala (Department of Kinesiology) and Dr. Philip Britz‐McKibbin of the Department of Chemistry.
Amos Raphenya and Pearl Guo have joined the McArthur Lab! Amos graduated from McMaster with Bachelor of Computer Engineering in 2008 and joins the lab as a core software engineer, for both our drug resistance and ecotoxicogenomics projects. Pearl just finished her second year at the University of Waterloo’s Computer Science co-op program, with a minor in Bioinformatics. Pearl will be performing a 3 month co-op position in the lab, with a focus on algorithms for prediction of glycopeptide resistance.
McMaster Innovation Showcase 2014 is an opportunity for the University to demonstrate the exciting technologies that have been developed at McMaster, feature the initiatives underway relating to entrepreneurship, and engage with the community.
When: November 12, 2014; 8:00am – 5:00pm Where: McMaster Innovation Park Atrium, First Floor
More information on Keynote address, roundtable discussion, and Open Doors can be found here.
Andrew McArthur will be returning to academia in September 2014 to join McMaster University as the Cisco Chair in Bioinformatics and Associate Professor in the Department of Biochemistry & Biomedical Sciences in the Faculty of Health Sciences. Read more about the McMaster – Cisco collaboration at: McMaster and Cisco collaborate to further bioinformatics research and build institutional research cloud.
McArthur Bioinformatics will be moving to Gothenburg, Sweden for 13 months starting July, 2012. During that time, Dr. McArthur will be a Guest Investigator in the Department of Biological & Environmental Sciences, University of Gothenburg in addition to his continuing consultancy work. All business matters will continue via the company’s Canadian address. His contact information remains unchanged.
In 2006, Dr. McArthur left academia to act as a consultant in computational biology and bioinformatics for researchers in academia and government. With researchers at the Woods Hole Oceanographic Institution (Woods Hole, MA), McMaster University (Hamilton, Canada), and the University of Alabama (Tuscaloosa, AL), he performed research in environmental toxicology, with emphasis on microarray and genomic investigation of the molecular response of adult and developing zebrafish to metal (e.g. metal stress transcription factor MTF-1), organic (e.g. tBHQ, TCDD), and pharmaceutical (acetaminophen, gemfibrozil, carbamazapine and venlafaxine) pollutants. These efforts have recently been expanded to include both computational and ChIP-Seq investigation of the involved regulatory mechanisms. Another major research area was in the construction of the Comprehensive Antibiotic Resistance Database with a consortium of academic and government researchers in Canada and the United Kingdom, based at McMaster University. This project involves sequencing and assembly of novel bacterial pathogen genomes using both 454 and Illumina technologies, and subsequent annotation of possible antibiotic resistance genes and mechanisms, with implications for clinical treatment. Lastly, additional efforts focussed on natural resources management, with development of algorithms for wildlife population genomics analysis.
After eight years in Woods Hole, Dr. McArthur and his family have made the decision to return to Canada in late May 2006. Over the 8 years in Woods Hole, Dr. McArthur progressed from Postdoctoral Researcher to Assistant Scientist, during which he established an active research program in Global Infectious Disease with funding from NIH/NIAID and the Ellison Medical Foundation. His examination of molecular approaches to difficult evolutionary questions led him to join the effort to sequence the entire 12 Mbp genome of the protistan parasite Giardia lamblia, hypothesized to be one of the oldest and most primitive eukaryotes alive. He was the lead computational biologist for the Giardia lamblia genome project, and principal investigator on NIH-funded Giardia lamblia, Trypanosoma brucei, and Schistosoma mansoni gene expression projects, which used Serial Analysis of Gene Expression (SAGE) to examine global gene expression in the context of parasite life cycles and the origins of virulence.
Thanks to all of our friends and colleagues in Woods Hole for eight wonderful years and special thanks to all of the past and present members of the McArthur lab who made research life at MBL fantastic!
Following up on his doctoral research, Dr. McArthur joined the NMNH as a Postdoctoral Fellow to use the tools of molecular systematics to test the hypothesis of ancient origins of deep-sea gastropods. This included his first serious foray into bioinformatics as part of the Laboratory of Molecular Systematics, with use of advanced algorithms for phylogenetic analysis.