Congratulations to our 3rd year Biochemistry & Biomedical Sciences students upon completion of their research projects! Both will be staying on as summer research students.
Tammy Lau – The Importance of Protocol Design for RNA-Seq in the Ongoing Development of a Novel Technology for Tissue Specific Gene Expression Profiling in C. elegans
Arjun Sharma – The Glycopeptide Resistance Predictor
Congratulations to 4th Year Biomedical Discovery & Commercialization student and McArthur lab member Suman Virdee for her CIHR Undergraduate Summer Studentship Award for her summer project “Development and implementation of computational tools to dissect cancer stem cell circuitry”, a joint project between our laboratory and that of Dr. Kristin Hope!
The McArthur lab and the Comprehensive Antibiotic Resistance Database are proud to have contributed to the Genome Canada – Canadian Food Inspection Agency Forum on Genomics and Antimicrobial Resistance. The two-day event brought together over sixty leading experts from academic, government, industry and commodities groups to address the challenge of AMR and discuss a path forward. A summary of the Forum and the Workshop Report are now online.
A cross-national research consortia co-led by McMaster’s Andrew McArthur is receiving two of 16 federal grants to further develop a big data solution to the growing problem of antimicrobial resistance (AMR). The government’s investment, totaling more than $4M, is the result of Genome Canada’s 2015 Bioinformatics and Computational Biology Competition, a partnership with the Canadian Institutes of Health Research (CIHR). McArthur and his colleagues will receive $500,000 over two years. McArthur will work closely with researchers from the University of British Columbia, Simon Fraser University, Dalhousie University and the Public Health Agency of Canada to design and develop novel software and database systems that will empower public health agencies and the agri-food sector to rapidly respond to threats posed by infectious disease outbreaks and food-borne illnesses.
CIHR (G. Steinberg, McMaster University, Canada) Gene Environment Team on Brown/beige Adipose Tissue (GET_BAT). In this project we will conduct studies in cells, mice and humans to examine how agricultural and food processing practices may regulate brown adipose tissue metabolic activity directly or indirectly by altering the billions of bacteria that reside within our gastrointestinal tract.
NIH/NIEHS (M. Jenny, University of Alabama, USA) The role of MTF-1 as a mediator of ocular toxicity. The major goals of this project are to characterize the role of MTF-1 in regulating genes involved in eye development.
NIH/NIEHS (A. Timme-Laragy, University of Massachusetts Amherst) Activation of Nrf2 during embryonic development: mechanisms and consequences. Examining the possible regulatory role of Nrf2 in early embryonic development, with emphasis upon molecular responses to oxidative stress.
Ten undergraduate students from the faculties of Science and Health Sciences have been awarded the prestigious Michael G. DeGroote Institute for Infectious Disease Research (IIDR) Summer Student Fellowship, including our own Briony Lago (third from the right). This highly competitive fellowship, now in its fourth year and worth $1,000, is designed to support students working in the labs of IIDR members during their summer practicum, which runs from May to August. Briony Lago joined the lab as part of her McMaster Chemical Biology Co-Op program, working on our ‘Omic’ Responses & Inactivity in Aging project (a collaboration with colleagues in Kinesiology & Chemistry), our collaboration with Bates College on the role of Nfe2 in oxidative stress response during zebrafish development, and biocuration of our Comprehensive Antibiotic Resistance Database.
Arjun Sharma is a 2cd year Biochemistry & Biomedical Sciences student how as a volunteer designed and created the new AMR Forums! Learn more about Arjun’s project at ‘New online AMR forum is a valuable learning resource’ or visit the AMR Forums.
Dr. McArthur gave a MacTalk at McMaster’s Big Ideas Better Cities evenings on Health and Social Innovation through Big Data about “Combatting antibiotic resistance using surveillance”. See the related How ‘Big Data’ can help solve big problems article at McMaster Daily News and the coverage at the Hamilton Spectator.