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Michael G. DeGroote Institute for Infectious Disease Research, McMaster University

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antibiotic resistance big data bioinformatics databases genomics publications software

Simultaneous detection of pathogens and antimicrobial resistance genes with the open source, cloud-based, CZ ID platform

May 8, 2025 agmcarthur

Lu et al. Genome Med. 2025 May 6;17(1):46. Background: Antimicrobial resistant (AMR) pathogens represent urgent threats to human health, and their surveillance is of paramount

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Congratulations Dr. Dirk Hackenberger!

April 24, 2025 agmcarthur

Antibiotics and Resistance: Past, Present, and Future By DIRK L HACKENBERGER, B.Sc. A thesis submitted to the school of graduate studies in partial fulfillment of

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Biochemistry & Biomedical Sciences Research Symposium 2025

March 30, 2025March 30, 2025 agmcarthur
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One Health: Antimicrobial Resistance and Emerging Zoonoses Conference

March 13, 2025March 13, 2025 agmcarthur

Wlodarski, M.A., T.T.Y. Lau, B.P. Alcock, A.R. Raphenya, F. Maguire, R.G. Beiko, T.E. Ta, & A.G. McArthur. 2025. Unmasking antibiotic resistance genes and their pathogen

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CARPDM: cost-effective antibiotic resistome profiling of metagenomic samples using targeted enrichment

February 28, 2025February 28, 2025 agmcarthur

Hackenberger et al. Appl Environ Microbiol. 2025 Feb 28:e0187624. Better interrogation of antimicrobial resistance requires new approaches to detect the associated genes in metagenomic samples.

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Post-Doc Update

February 16, 2025February 26, 2025 agmcarthur

Two alumni of the McMaster Biochemistry graduate program have joined the McArthur Lab! Dr. Emily Bordeleau got her PhD from McMaster in 2022 under the

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McMaster researchers develop new, publicly accessible AI tool to help scientists find new antibiotics

January 27, 2025January 27, 2025 agmcarthur

Jon Stokes (left) and graduate student Autumn Arnold (right) are excited to launch the ESKAPE Model, an all-new AI tool designed to help the global

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3rd Annual Antimicrobial Resistance Symposium

November 21, 2024November 21, 2024 agmcarthur

Mateusz Wlodarski wins the bioMerieux prize for best poster presentation! Arnold, A., A.R. Raphenya, A.G. McArthur, & J.M. Stokes. 2024. The ESKAPE model: AI-guided antibiotic

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IIDR Trainee Day 2024!

November 17, 2024November 17, 2024 agmcarthur

A great day of posters and presentations by the trainees of the Michael G. DeGroote Institute of Infectious Disease Research! Nilasha Mohan, Undergraduate student. Developing

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antibiotic resistance big data genomics publications

Diversity, functional classification and genotyping of SHV β-lactamases in Klebsiella pneumoniae

October 22, 2024 agmcarthur

Tsang et al. Microb Genom. 2024 Oct;10(10). Interpreting the phenotypes of bla SHV alleles in Klebsiella pneumoniae genomes is complex. Whilst all strains are expected

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ASM NGS Meeting 2024

October 15, 2024October 15, 2024 agmcarthur

Wlodarski, M.A., T.T.Y. Lau, A.R. Raphenya, B.P. Alcock, & A.G. McArthur. 2024. Accurate pathogen-of-origin classification of antibiotic resistance genes with CARD k-mers. Presentation at the

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ID-IIDR Rounds

October 2, 2024October 6, 2024 agmcarthur

This one-hour webinar, entitled “DNA sequencing in infectious disease surveillance, diagnosis, and management,” features talks from Andrew McArthur (Professor, Biochemistry and Biomedical Sciences) and Rubayet

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CSM, EDAR7, & more!

July 23, 2024July 24, 2024 agmcarthur

  CSM Mukiri, K.M., B.P. Alcock, & A.G. McArthur. 2024. Increasing the predictive accuracy of the Resistance Gene Identifier by abandoning sole reliance on bitscore.

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Pre-Prints 2024!

May 10, 2024June 3, 2024 agmcarthur

Gill, E.E., B. Jia, C.L. Murall, R. Poujol, M.Z. Anwar, N.S. John, J. Richardsson, A. Hobb, A.S. Olabode, A. Lepsa, A.T. Duggan, A.D. Tyler, A.

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Presentations at the AMMI-CACMID 2024 Conference

April 13, 2024May 10, 2024 agmcarthur

Alcock, B.P., E.A. Bordeleau, & A.G McArthur. 2024. Improving aminoglycoside resistance surveillance and stewardship efforts through nomenclature harmonization with the Comprehensive Antibiotic Resistance Database. Presentation

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Antimicrobial Resistance – Genomes, Big Data and Emerging Technologies – Wellcome Trust, UK

March 15, 2024March 15, 2024 agmcarthur

Mukiri, K.M., B.P. Alcock, & A.G. McArthur. 2024. Increasing the predictive accuracy of the Resistance Gene Identifier by abandoning sole reliance on bitscore. Ta, T.E.,

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antibiotic resistance genomics publications

Minimal impact on the resistome of children in Botswana after azithromycin treatment for acute severe diarrhoeal disease

February 3, 2024February 3, 2024 agmcarthur

Allison K Guitor, Anna Katyukhina, Margaret Mokomane, Kwana Lechiile, David M Goldfarb, Gerard D Wright, Andrew G McArthur, & Jeffrey M Pernica J Infect Dis.

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A standardized nomenclature for resistance-modifying agents in the Comprehensive Antibiotic Resistance Database

November 20, 2023November 20, 2023 agmcarthur

Keaton W Smith, Brian P Alcock, Shawn French, Maya A Farha, Amogelang R Raphenya, Eric D Brown, & Andrew G McArthur. Microbiol Spectrum. 2023 Nov

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IIDR Trainee Day 2023

November 13, 2023November 13, 2023 agmcarthur

COLIN BRUCE – Investigating Fibre Degradation in the Infant Gut Microbiota ; DIRK HACKENBERGER – Was World War 2 Foundational to the Antimicrobial Resistance Crisis?

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Welcome Dr. Brody Duncan!

September 1, 2023August 28, 2023 agmcarthur

The McArthur lab welcomes Brody Duncan, M.D. (Hamilton Health Sciences) as he starts his M.Sc. studies with us, investigating standards and methods for clinical reporting

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