Antibiotics and Resistance: Past, Present, and Future By DIRK L HACKENBERGER, B.Sc. A thesis submitted to the school of graduate studies in partial fulfillment of
Category: antibiotic resistance
Wlodarski, M.A., T.T.Y. Lau, B.P. Alcock, A.R. Raphenya, F. Maguire, R.G. Beiko, T.E. Ta, & A.G. McArthur. 2025. Unmasking antibiotic resistance genes and their pathogen
Hackenberger et al. Appl Environ Microbiol. 2025 Feb 28:e0187624. Better interrogation of antimicrobial resistance requires new approaches to detect the associated genes in metagenomic samples.
Two alumni of the McMaster Biochemistry graduate program have joined the McArthur Lab! Dr. Emily Bordeleau got her PhD from McMaster in 2022 under the
Jon Stokes (left) and graduate student Autumn Arnold (right) are excited to launch the ESKAPE Model, an all-new AI tool designed to help the global
Mateusz Wlodarski wins the bioMerieux prize for best poster presentation! Arnold, A., A.R. Raphenya, A.G. McArthur, & J.M. Stokes. 2024. The ESKAPE model: AI-guided antibiotic
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IIDR Trainee Day 2024!
A great day of posters and presentations by the trainees of the Michael G. DeGroote Institute of Infectious Disease Research! Nilasha Mohan, Undergraduate student. Developing
Tsang et al. Microb Genom. 2024 Oct;10(10). Interpreting the phenotypes of bla SHV alleles in Klebsiella pneumoniae genomes is complex. Whilst all strains are expected
Wlodarski, M.A., T.T.Y. Lau, A.R. Raphenya, B.P. Alcock, & A.G. McArthur. 2024. Accurate pathogen-of-origin classification of antibiotic resistance genes with CARD k-mers. Presentation at the
This one-hour webinar, entitled “DNA sequencing in infectious disease surveillance, diagnosis, and management,” features talks from Andrew McArthur (Professor, Biochemistry and Biomedical Sciences) and Rubayet
CSM Mukiri, K.M., B.P. Alcock, & A.G. McArthur. 2024. Increasing the predictive accuracy of the Resistance Gene Identifier by abandoning sole reliance on bitscore.
Gill, E.E., B. Jia, C.L. Murall, R. Poujol, M.Z. Anwar, N.S. John, J. Richardsson, A. Hobb, A.S. Olabode, A. Lepsa, A.T. Duggan, A.D. Tyler, A.
Alcock, B.P., E.A. Bordeleau, & A.G McArthur. 2024. Improving aminoglycoside resistance surveillance and stewardship efforts through nomenclature harmonization with the Comprehensive Antibiotic Resistance Database. Presentation
antibiotic resistance big data bioinformatics databases genomics molecular epidemiology presentations
Antimicrobial Resistance – Genomes, Big Data and Emerging Technologies – Wellcome Trust, UK
Mukiri, K.M., B.P. Alcock, & A.G. McArthur. 2024. Increasing the predictive accuracy of the Resistance Gene Identifier by abandoning sole reliance on bitscore. Ta, T.E.,
Allison K Guitor, Anna Katyukhina, Margaret Mokomane, Kwana Lechiile, David M Goldfarb, Gerard D Wright, Andrew G McArthur, & Jeffrey M Pernica J Infect Dis.
Keaton W Smith, Brian P Alcock, Shawn French, Maya A Farha, Amogelang R Raphenya, Eric D Brown, & Andrew G McArthur. Microbiol Spectrum. 2023 Nov
antibiotic resistance big data bioinformatics databases epidemiology genomics IIDR lab members molecular epidemiology ontologies presentations software text mining
IIDR Trainee Day 2023
COLIN BRUCE – Investigating Fibre Degradation in the Infant Gut Microbiota ; DIRK HACKENBERGER – Was World War 2 Foundational to the Antimicrobial Resistance Crisis?
The McArthur lab welcomes Brody Duncan, M.D. (Hamilton Health Sciences) as he starts his M.Sc. studies with us, investigating standards and methods for clinical reporting
Baker, S.J.C., J. Maciejewski, M.-T. Usuanlele, J. Gilchrist, D.R. Sharma, D. Bulir, M. Smieja, M. Loeb, M.G. Surette, A.G. McArthur, & D. Mertz. 2023. Investigating