Hackenberger et al. Appl Environ Microbiol. 2025 Feb 28:e0187624. Better interrogation of antimicrobial resistance requires new approaches to detect the associated genes in metagenomic samples.
Category: publications
This week we say farewell to Dr. Sheridan Baker, who joined us in early 2021 as lead molecular biologist for our Ontario Genomics Coalition (ONCoV)
Nirmalarajah et al. BMC Infect Dis. 2025 Jan 28;25(1):132. Background: Drivers of COVID-19 severity are multifactorial and include multidimensional and potentially interacting factors encompassing viral
Nasir et al. NAR Genomics & Bioinformatics. 2024 Dec 18;6(4):lqae176. The incorporation of sequencing technologies in frontline and public health healthcare settings was vital in
Tsang et al. Microb Genom. 2024 Oct;10(10). Interpreting the phenotypes of bla SHV alleles in Klebsiella pneumoniae genomes is complex. Whilst all strains are expected
Gill et al. 2024. The Canadian VirusSeq Data Portal & Duotang: open resources for SARS-CoV-2 viral sequences and genomic epidemiology. Microb Genom. 2024 Oct;10(10):001293. The
Gill, E.E., B. Jia, C.L. Murall, R. Poujol, M.Z. Anwar, N.S. John, J. Richardsson, A. Hobb, A.S. Olabode, A. Lepsa, A.T. Duggan, A.D. Tyler, A.
Allison K Guitor, Anna Katyukhina, Margaret Mokomane, Kwana Lechiile, David M Goldfarb, Gerard D Wright, Andrew G McArthur, & Jeffrey M Pernica J Infect Dis.
clinical metadata COVID19 genomics molecular epidemiology publications SARS-CoV-2 virus epidemiology
Chronic COVID-19 infection in an immunosuppressed patient shows changes in lineage over time: a case report
Sheridan J C Baker , Landry E Nfonsam , Daniela Leto , Candy Rutherford , Marek Smieja , & Andrew G McArthur Virol J. 2024
Day, E.A., L.K. Townsend, S. Rehal, B. Batchuluun, D. Wang, M.R. Morrow, R. Lu, L. Lundenberg, J.H. Lu, E.M. Desjardins, A.R. Raphenya, A.G. McArthur, M.D.
Keaton W Smith, Brian P Alcock, Shawn French, Maya A Farha, Amogelang R Raphenya, Eric D Brown, & Andrew G McArthur. Microbiol Spectrum. 2023 Nov
Jacob et al. Emerg Infect Dis. 2023 Jun 12;29(7). Isolating and characterizing emerging SARS-CoV-2 variants is key to understanding virus pathogenesis. In this study, we
Tsang et al. Microbiol Spectr. 2023 Apr 24;e0190022. Genomic epidemiology can facilitate an understanding of evolutionary history and transmission dynamics of a severe acute respiratory
Arman Edalatmand & Andrew G McArthur. 2023. Database, doi: 10.1093/database/baad023. Scientific literature is published at a rate that makes manual data extraction a highly time-consuming
Alcock et al. 2023. Nucleic Acids Res Oct 20, 2022:gkac920. (online ahead of print) The Comprehensive Antibiotic Resistance Database (CARD; card.mcmaster.ca) combines the Antibiotic Resistance
Guitor et al. 2022. Microbiome 10(1):136. Background: Probiotic use in preterm infants can mitigate the impact of antibiotic exposure and reduce rates of certain illnesses;
big data clinical metadata epidemiology molecular epidemiology publications SARS-CoV-2 virus epidemiology
The Dataharmonizer: a Tool for Faster Data Harmonization, Validation, Aggregation, and Analysis of Pathogen Genomics Contextual Information
Gill et al. 2022. Preprints 10.20944/preprints202206.0335.v1 Pathogen genomics is a critical tool for public health surveillance, infection control, outbreak investigations, as well as research. In
Raphenya et al. Scientific Data volume 9, Article number: 341 (2022). Whole genome sequencing (WGS) is a key tool in identifying and characterising disease-associated bacteria
Rooney et al. 2022 Jun 1;e0002222. Short-read sequencing can provide detection of multiple genomic determinants of antimicrobial resistance from single bacterial genomes and metagenomic samples.
Kim et al. Clin Microbiol Rev. 2022 May 25;e0017921. Antimicrobial resistance (AMR) is a global health crisis that poses a great threat to modern medicine.