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Michael G. DeGroote Institute for Infectious Disease Research, McMaster University

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Congratulations finishing thesis students!

April 6, 2020December 30, 2020 agmcarthur

COVID19 kept us from celebrating together, but we are very proud of the work you have accomplished! Rachel Tran | Biochem 4T15 – Exploring the

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lab members

Congratulations Sohaib Syed!

March 26, 2020December 30, 2020 agmcarthur

Congratulations to lab member Sohaib Syed and the team at Bisep for winning the 2002 Synapse Competition! Innovation Factory awards $100,000 in cash and in-kind

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antibiotic resistance COVID19 epidemiology genomics lab members molecular epidemiology news SARS-CoV-2 virus epidemiology

McArthur Lab & CARD during SARS-CoV-2

March 23, 2020December 30, 2020 agmcarthur

Quick update on the status of the McArthur Lab and the Comprehensive Antibiotic Resistance Database. While our home institution McMaster University is closed to on-site

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genomics molecular epidemiology software worth reading

Preprint: Rapid design of a bait capture platform for culture- and amplification-free next-generation sequencing of SARS-CoV-2

February 26, 2020December 30, 2020 agmcarthur

Nasir, J.A., D.J. Speicher, R.A. Kozak, H.N. Poinar, M.S. Miller, & A.G. McArthur. Preprints 2020, 2020020385. SARS-CoV-2 is a novel betacoronavirus and the aetiological agent

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antibiotic resistance databases publications

Detection of Antimicrobial Resistance Using Proteomics and the Comprehensive Antibiotic Resistance Database: a Case Study

December 26, 2019December 30, 2020 agmcarthur

Chen CY, Clark CG, Langner S, Boyd DA, Bharat A, McCorrister SJ, McArthur AG, Graham MR, Westmacott GR, Van Domselaar G Proteomics Clin Appl. 2019

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publications

Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss

December 10, 2019December 30, 2020 agmcarthur

Day EA, Ford RJ, Smith BK, Mohammadi-Shemirani P, Morrow MR, Gutgesell RM, Lu R, Raphenya AR, Kabiri M, McArthur AG, McInnes N, Hess S, Paré

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molecular epidemiology phylogenetics publications

An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp

November 6, 2019December 30, 2020 agmcarthur

Ahmad S, Wang B, Walker MD, Tran H-KR, Stogios PJ, Savchenko A, Grant RA, McArthur AG, Laub MT, Whitney JC Nature 2019 Nov 6. [Epub

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antibiotic resistance big data bioinformatics databases epidemiology genomics molecular epidemiology ontologies publications

CARD 2020: antibiotic resistome surveillance with the Comprehensive Antibiotic Resistance Database

October 30, 2019December 30, 2020 agmcarthur

Alcock BP, Raphenya AR, Lau TTY, Tsang KK, Bouchard M, Edalatmand A, Huynh W, Nguyen A-LV, Cheng AA, Liu S, Min SY, Miroshnichenko A, Tran

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antibiotic resistance genomics publications

Capturing the Resistome: A targeted capture method to reveal antibiotic resistance determinants in metagenomes

October 16, 2019December 30, 2020 agmcarthur

Guitor AK, Raphenya AR, Klunk J, Kuch M, Alcock B, Surette MG, McArthur AG, Poinar HN, Wright GD. Editor’s Pick! Antimicrobial Agents and Chemotherapy 2019 Oct

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awards IIDR lab members presentations

IIDR Trainee Day 2019

October 5, 2019December 30, 2020 agmcarthur

Edalatmand, A. & A.G. McArthur. 2019. Classifying and curating publications on antimicrobial resistance using machine learning. Poster presentation at the Michael G. DeGroote Institute for

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awards IIDR lab members

Congratulations Amos Raphenya & Rachel Tran!

October 5, 2019December 30, 2020 agmcarthur

The McArthur Lab is very proud to announce Amos Raphenya as 2019 IIDR Michael Kamin Kart Memorial Scholarship Recipient (Staff) and Rachel Tran as 2019

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lab members news

McArthur Lab 2019-2020

September 5, 2019December 30, 2020 agmcarthur

(left to right) Back row: Amos Raphenya, Arman Edalatmand, Brian Alcock, Andrew McArthur, David Speicher, Martins Oloni, Sohaib Syed. Front row: William Huynh, Anna-Lisa Nguyen,

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lab members news

Jalees Nasir, Ph.D. Student

September 1, 2019December 30, 2020 agmcarthur

Jalees Nasir transferred from the McMaster Biochemistry & Biomedical Sciences Masters program to the Ph.D. program today! Jalees’s work focusses on the developing new genomic

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antibiotic resistance big data bioinformatics genomics IIDR publications

Phylogenetic reconciliation reveals the natural history of glycopeptide antibiotic biosynthesis and resistance

August 19, 2019December 30, 2020 agmcarthur

Waglechner N, McArthur AG, Wright GD. Nat Microbiol. 2019 Aug 12. [Epub ahead of print] Glycopeptide antibiotics are produced by Actinobacteria through biosynthetic gene clusters

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parasitology publications

PCR detection of mixed and zoonoses Malaria using Plasmodium spp dynein light chain (dlc-tctex) gene

August 6, 2019December 30, 2020 agmcarthur

Kariuki MW, Githui E, McArthur AG, Aman RA, Njagi NM, Mwangemi AC, Kamau LW Annual Research & Review in Biology, 32, 1-12. Novel gene targets

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presentations

Summer Conferences 2019!

August 1, 2019December 30, 2020 agmcarthur

Maguire, F., B. Alcock, A.R. Raphenya, B. Jia. E.J. Griffiths, T.C. Matthews, J. Adam, A. Petkau, G.L. Winsor, IRIDA Consortium, R.G. Beiko, F.S.L. Brinkman, W.W.L.

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publications

Preprints!

July 19, 2019December 30, 2020 agmcarthur

Faltyn, M., B. Alcock, & A.G. McArthur. 2019. Evolution and nomenclature of the trimethoprim resistant dihydrofolate (dfr) reductases. Preprints 2019, 2019050137. [Preprint] Tsang, K.K., D.J.

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BDC

Dr. McArthur, Director of the Biomedical Discovery & Commercialization Program

July 1, 2019December 30, 2020 agmcarthur

Learn about the BDC program here.

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antibiotic resistance IIDR McMaster news worth reading

McArthur Lab joins the David Braley Centre for Antibiotic Discovery!

June 24, 2019December 30, 2020 agmcarthur

David Braley Centre for Antibiotic Discovery gives researchers a fighting chance against antimicrobial resistance. A forward-looking McMaster donor is investing $7 million in a new

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antibiotic resistance genomics

Some Recent Funding News…

June 6, 2019January 8, 2021 agmcarthur

Empowering conventional antibiotics with new drug leads targeting the outer-membrane of Gram-negative pathogens. E. Brown (PI), G.D. Wright (co-I), B. Coombes (co-I), A.G. McArthur (co-I),

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