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Michael G. DeGroote Institute for Infectious Disease Research, McMaster University

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kinesiology publications

Failed recovery of glycemic control and myofibrillar protein synthesis with 2 wk of physical inactivity in overweight, prediabetic older adults.

July 16, 2018December 30, 2020 agmcarthur

McGlory C, von Allmen MT, Stokes T, Morton RW, Hector AJ, Lago BA, Raphenya AR, Smith BK, McArthur AG, Steinberg GR, Baker SK, Phillips SM

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population genomics publications

Genetic population structure of the round whitefish (Prosopium cylindraceum) in North America: multiple markers reveal glacial refugia and regional subdivision

May 25, 2018December 30, 2020 agmcarthur

Morgan TD, Graham CF, McArthur AG, Raphenya AR, Boreham DR, Manzon RG, Wilson JY, Lance SL, Howland KL, Patrick PH, Somers CM Canadian Journal of

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phylogenetics publications

Functional relatedness in the Inv/Mxi-Spa Type III secretion system family

March 13, 2017December 30, 2020 agmcarthur

Klein JA, Dave BM, Raphenya AR, McArthur AG, Knodler LA. Mol Microbiol. 2017 Mar;103(6):973-991. Type III Secretion Systems (T3SSs) are structurally conserved nanomachines that span

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antibiotic resistance bioinformatics databases ontologies publications

Antimicrobial resistance surveillance in the genomic age

February 14, 2017December 30, 2020 agmcarthur

McArthur AG & Tsang KK. Ann N Y Acad Sci. 2017 Jan;1388(1):78-91. The loss of effective antimicrobials is reducing our ability to protect the global population from

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antibiotic resistance big data bioinformatics databases publications

CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database.

January 4, 2017December 30, 2020 agmcarthur

Jia B, Raphenya AR, Alcock B, Waglechner N, Guo P, Tsang KK, Lago BA, Dave BM, Pereira S, Sharma AN, Doshi S, Courtot M, Lo

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antibiotic resistance genomics publications

A diverse intrinsic antibiotic resistome from a cave bacterium

December 8, 2016December 30, 2020 agmcarthur

Pawlowski AC, Wang W, Koteva K, Barton HA, McArthur AG, & Wright GD. Nat Commun. 2016 Dec 8;7:13803. Antibiotic resistance is ancient and widespread in

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antibiotic resistance news publications

Forum on Genomics and Antimicrobial Resistance – Workshop Report

December 1, 2016December 30, 2020 agmcarthur

The McArthur lab and the Comprehensive Antibiotic Resistance Database are proud to have contributed to the Genome Canada – Canadian Food Inspection Agency Forum on

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antibiotic resistance big data bioinformatics publications

YphC and YsxC GTPases assist the maturation of the central protuberance, GTPase associated region and functional core of the 50S ribosomal subunit

October 11, 2016December 30, 2020 agmcarthur

Ni X, Davis JH, Jain N, Razi A, Benlekbir S, McArthur AG, Rubinstein JL, Britton RA, Williamson JR, Ortega J. Nucleic Acids Res. 2016 Sep

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ecotoxicogenomics publications

The transcription factor, Nuclear factor, erythroid 2 (Nfe2), is a regulator of the oxidative stress response during Danio rerio development

October 11, 2016December 30, 2020 agmcarthur

Williams LM, Lago BA, McArthur AG, Raphenya AR, Pray N, Saleem N, Salas S, Paulson K, Mangar RS, Liu Y, Vo AH, Shavit JA. Aquat

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population genomics publications

Gene duplication and divergence produce divergent MHC genotypes without disassortative mating

September 15, 2016December 30, 2020 agmcarthur

Authors: Dearborn DC, Gager AB, McArthur AG, Gilmour ME, Mandzhukova E, Mauck RA. Mol Ecol. 2016 Sep;25(17):4355-67. Genes of the major histocompatibility complex (MHC) exhibit

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antibiotic resistance lab members publications

Recent McArthur Lab Presentations and Posters

June 14, 2016December 31, 2020 agmcarthur

McMaster Interdisciplinary Research Exposition (MIREx); Ontario Biology Day; Biomedical Discovery and Commercialization Engage Symposium; Rapid Microbial NGS and Bioinformatics: Translation Into Practice (Germany); Canadian Food Inspection Agency Forum on

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antibiotic resistance epidemiology genomes genomics publications

Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

October 21, 2015December 31, 2020 agmcarthur

Authors: Freschi et al. Front Microbiol. 2015 Sep 29;6:1036. The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes and building an analysis pipeline for the study

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genomics population genomics publications

Impacts of degraded DNA on restriction enzyme associated DNA sequencing (RADSeq)

October 13, 2015December 31, 2020 agmcarthur

Authors: Graham CF, Glenn TC, McArthur AG, Boreham DR, Kieran T, Lance S, Manzon RG, Martino JA, Pierson T, Rogers SM, Wilson JY, Somers CM. Mol Ecol

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antibiotic resistance big data databases epidemiology publications

Bioinformatics of antimicrobial resistance in the age of molecular epidemiology

July 31, 2015December 31, 2020 agmcarthur

Authors: McArthur AG, Wright GD. Curr Opin Microbiol. 2015 Jul 31;27:45-50. Antimicrobial resistance is a global health challenge and has an evolutionary trajectory ranging from

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antibiotic resistance databases genomes publications

IslandViewer 3: more flexible, interactive genomic island discovery, visualization and analysis

July 8, 2015December 31, 2020 agmcarthur

Authors: Dhillon BK, Laird MR, Shay JA, Winsor GL, Lo R, Nizam F, Pereira SK, Waglechner N, McArthur AG, Langille MG, Brinkman FS. Nucleic Acids Res.

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population genomics publications

Non-neutral evolution and reciprocal monophyly of two expressed Mhc class II B genes in Leach’s storm-petrel

January 26, 2015December 31, 2020 agmcarthur

Authors: Dearborn DC, Gager AB, Gilmour ME, McArthur AG, Hinerfeld DA, Mauck RA. Immunogenetics. 2015 Feb;67(2):111-23. The major histocompatibility complex (Mhc) is subject to pathogen-mediated

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parasitology publications

Gene expression changes during Giardia-host cell interactions in serum-free medium

December 4, 2014December 31, 2020 agmcarthur

Authors: Ferella M, Davids BJ, Cipriano MJ, Birkeland SR, Palm D, Gillin FD, McArthur AG, Svärd S. Mol Biochem Parasitol. 2014 Oct;197(1-2):21-3. Serial Analysis of

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ecotoxicogenomics publications

The Transcriptional Response to Oxidative Stress during Vertebrate Development: Effects of tert-Butylhydroquinone and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

November 18, 2014December 31, 2020 agmcarthur

Authors: Hahn ME, McArthur AG, Karchner SI, Franks DG, Jenny MJ, Timme-Laragy AR, Stegeman JJ, Woodin BR, Cipriano MJ, Linney E. PLoS One. 2014 Nov 17;9(11):e113158.

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ecotoxicogenomics publications

Inhibition of endogenous MTF-1 signaling in zebrafish embryos identifies novel roles for MTF-1 in development

June 26, 2014December 31, 2020 agmcarthur

Authors: O’Shields B, McArthur AG, Holowiecki A, Kamper M, Tapley J, Jenny MJ Biochim Biophys Acta. 2014 Apr 18;1843(9):1818-1833 The metal responsive element-binding transcription factor-1

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ecotoxicogenomics publications

Developmental expression of the Nfe2-related factor (Nrf) transcription factor family in the zebrafish, Danio rerio

December 5, 2013December 31, 2020 agmcarthur

Authors: Williams LM, Timme-Laragy AR, Goldstone JV, McArthur AG, Stegeman JJ, Smolowitz RM, Hahn ME PLoS One. 2013 Oct 24;8(10):e79574 Transcription factors in the CNC-bZIP

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