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Michael G. DeGroote Institute for Infectious Disease Research, McMaster University

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Arman Edalatmand wins a MacData Fellowship!

March 30, 2021May 4, 2021 agmcarthur

Arman Edalatmand has been awarded a 2021 MacData Fellowship from McMaster’s MacData Institute. Working with co-supervisors Drs. Andrew McArthur (Biochemistry & Biomedical Sciences) and Victor

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WISE CREST, Ontario Biology Day, BBS Research Symposium 2021

March 24, 2021March 25, 2021 agmcarthur

McMaster Biochemistry & Biomedical Sciences Research Symposium Edalatmand. A. & A.G. McArthur. 2021. Ontology-driven method of contextualizing antimicrobial resistance determinants. Poster presentation at the McMaster

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OpEd: SARS-CoV-2 variants of concern remind us that we underestimate biology at our own peril

March 16, 2021March 16, 2021 agmcarthur

Imagine a tiny molecular machine armed with a program to infect human cells, subvert their defenses and make copies of itself to infect neighboring cells

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Welcome Sheridan Baker

February 4, 2021May 4, 2021 agmcarthur

As part of our continuing efforts on genomic surveillance of SARS-CoV-2 variants for CanCOGeN, the McArthur lab welcomes Sheridan Baker, who will be doing the

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Genomic Epidemiology of SARS-CoV-2: Canada & Ontario

January 15, 2021January 15, 2021 agmcarthur

In collaboration with our colleague Dr. Finlay Maguire (Dalhousie University) and as part of our ongoing work for Ontario’s COVID-19 Genomics Rapid Response Coalition and the Canadian

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Amos Raphenya, MSc Student

January 14, 2021 agmcarthur

It is with great pleasure the McArthur lab announces that Lead Developer for the Comprehensive Antibiotic Resistance Database (CARD), Amos Raphenya, is starting his M.Sc.

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antibiotic resistance big data genomics publications

Identifying novel β-lactamase substrate activity through in silico prediction of antimicrobial resistance

January 8, 2021January 8, 2021 agmcarthur

Kara K. Tsang, Finlay Maguire, Haley L. Zubyk, Sommer Chou, Arman Edalatmand, Gerard D. Wright, Robert G. Beiko, & Andrew G. McArthur Microbial Genomics, in

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Bacterial type VII secretion: an important player in host‐microbe and microbe‐microbe interactions

January 8, 2021January 8, 2021 agmcarthur

Hiu‐Ki R. Tran, Dirk W. Grebenc, Timothy A. Klein, John C. Whitney Molecular Microbiology, in press. Type VII secretion systems (T7SSs) are poorly understood protein

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bioinformatics genomics molecular epidemiology publications virulence

Whole genome sequence of Corynebacterium kroppenstedtii isolated from a case of recurrent granulomatous mastitis

December 29, 2020February 7, 2021 agmcarthur

Charlie Tan, Fang-I Lu, Patryk Aftanas, Kara Tsang, Samira Mubareka, Adrienne Chan, & Robert Kozak IDCases. 2020. 23:e01034. We describe the case of a 33-year-old

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antibiotic resistance genomics publications

Recurrent multidrug-resistant Salmonella enterica serovar Typhimurium bacteremia in a returned traveller

December 16, 2020December 30, 2020 agmcarthur

Adam S Komorowski, Xena X Li, Eva Piessens, Andrew G McArthur, & Ameen Patel Journal of the Association of Medical Microbiology and Infectious Disease Canada,

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bioinformatics genomics publications virulence

Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones

December 16, 2020December 30, 2020 agmcarthur

Shehryar Ahmad, Kara L Tsang, Kartik Sachar, Dennis Quentin, Tahmid M Tashin, Nathan P Bullen, Stefan Raunser, Andrew G McArthur, Gerd Prehna, & John C

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ASMNGS 2020 Virtual Conference – 4th ASM Conference on Rapid Applied Microbial Next-Generation Sequencing and Bioinformatic Pipelines

December 10, 2020December 30, 2020 agmcarthur

Aaron Petkau performed his Visual & Automated Disease Analytics Program internship (Univ. of Manitoba) with us during the summer of 2020, creating the CARD:Live graphic

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COVID19 publications

A regional Canadian expert consensus on recommendations for restoring exercise and pulmonary function testing in low and moderate-to-high community prevalence coronavirus disease 2019 (COVID-19) settings

November 20, 2020December 30, 2020 agmcarthur

Sarah Khan, Kara K Tsang, Dominik Mertz, Myrna Dolovich, Marcel Tunks, Catherine Demers, Kelly Hassall, Neil Maharaj, Karen Margallo, Maureen Cividino, Zain Chagla, & MyLinh

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IIDR Trainee Day 2020! Forging the Future of Infectious Disease Research

November 11, 2020December 30, 2020 agmcarthur

Nasir, J.A et al. 2020. SIGNALing the Need for Surveillance: A Comparison of Whole Genome Sequencing Methods for SARS-CoV-2. Edalatmand, A. & A.G. McArthur. 2020.

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COVID19 publications

Silver linings of the COVID-19 pandemic from an infection prevention and control perspective

November 10, 2020December 30, 2020 agmcarthur

Kara K Tsang, Dominik Mertz, Cindy O’Neill, & Sarah Khan Infect Control Hosp Epidemiol. 2020 Nov 4;1-7. As the COVID-19 pandemic evolved, infection prevention and

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publications

De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors

November 8, 2020December 30, 2020 agmcarthur

Workenhe, S.T., A. Nguyen, D. Bakhshinyan, J. Wei, D.N. Hare, K.L. MacNeill, Y. Wan, A. Oberst, J.L. Bramson, J.A. Nasir, S.K. Singh, A.G. McArthur, &

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International NEXUS for Pandemics and Biological Threats, Canadian Chemical Compound Library for Antibiotic Discovery, and $1.475M CFI Funding

November 6, 2020December 30, 2020 agmcarthur

McMaster is launching The Global Nexus for Pandemics and Biological Threats, to ensure Canada and the world are better able to manage the human and

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McArthur Lab & McMaster contribute to global genomic surveillance of SARS-CoV-2

October 21, 2020December 30, 2020 agmcarthur

 

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Cisco McMaster Mitacs

Some Recent Funding News…

October 20, 2020December 30, 2020 agmcarthur

Assessing the viability of whole genome bisulfite-sequencing for epigenetic age prediction. A.G. McArthur (PI), M. Chong (Intern). Mitacs Accelerate. Drug Metabolism in the human microbiome.

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Congratulations Martins Oloni!

September 11, 2020December 30, 2020 agmcarthur

Congratulations Martins Oloni on the successful defence of your Masters of Science! New Delhi Metallo-Beta-Lactamase (NDM) plasmid predictions The complete detection and genome sequencing of

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