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Michael G. DeGroote Institute for Infectious Disease Research, McMaster University

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antibiotic resistance big data genomics publications

Identifying novel β-lactamase substrate activity through in silico prediction of antimicrobial resistance

January 8, 2021January 8, 2021 agmcarthur

Kara K. Tsang, Finlay Maguire, Haley L. Zubyk, Sommer Chou, Arman Edalatmand, Gerard D. Wright, Robert G. Beiko, & Andrew G. McArthur Microbial Genomics, in

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lab members publications virulence

Bacterial type VII secretion: an important player in host‐microbe and microbe‐microbe interactions

January 8, 2021January 8, 2021 agmcarthur

Hiu‐Ki R. Tran, Dirk W. Grebenc, Timothy A. Klein, John C. Whitney Molecular Microbiology, in press. Type VII secretion systems (T7SSs) are poorly understood protein

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bioinformatics genomics molecular epidemiology publications virulence

Whole genome sequence of Corynebacterium kroppenstedtii isolated from a case of recurrent granulomatous mastitis

December 29, 2020February 7, 2021 agmcarthur

Charlie Tan, Fang-I Lu, Patryk Aftanas, Kara Tsang, Samira Mubareka, Adrienne Chan, & Robert Kozak IDCases. 2020. 23:e01034. We describe the case of a 33-year-old

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antibiotic resistance genomics publications

Recurrent multidrug-resistant Salmonella enterica serovar Typhimurium bacteremia in a returned traveller

December 16, 2020December 30, 2020 agmcarthur

Adam S Komorowski, Xena X Li, Eva Piessens, Andrew G McArthur, & Ameen Patel Journal of the Association of Medical Microbiology and Infectious Disease Canada,

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bioinformatics genomics publications virulence

Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones

December 16, 2020December 30, 2020 agmcarthur

Shehryar Ahmad, Kara L Tsang, Kartik Sachar, Dennis Quentin, Tahmid M Tashin, Nathan P Bullen, Stefan Raunser, Andrew G McArthur, Gerd Prehna, & John C

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COVID19 publications

A regional Canadian expert consensus on recommendations for restoring exercise and pulmonary function testing in low and moderate-to-high community prevalence coronavirus disease 2019 (COVID-19) settings

November 20, 2020December 30, 2020 agmcarthur

Sarah Khan, Kara K Tsang, Dominik Mertz, Myrna Dolovich, Marcel Tunks, Catherine Demers, Kelly Hassall, Neil Maharaj, Karen Margallo, Maureen Cividino, Zain Chagla, & MyLinh

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COVID19 publications

Silver linings of the COVID-19 pandemic from an infection prevention and control perspective

November 10, 2020December 30, 2020 agmcarthur

Kara K Tsang, Dominik Mertz, Cindy O’Neill, & Sarah Khan Infect Control Hosp Epidemiol. 2020 Nov 4;1-7. As the COVID-19 pandemic evolved, infection prevention and

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publications

De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors

November 8, 2020December 30, 2020 agmcarthur

Workenhe, S.T., A. Nguyen, D. Bakhshinyan, J. Wei, D.N. Hare, K.L. MacNeill, Y. Wan, A. Oberst, J.L. Bramson, J.A. Nasir, S.K. Singh, A.G. McArthur, &

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COVID19 publications SARS-CoV-2 virus epidemiology

Predicting the recombination potential of severe acute respiratory syndrome coronavirus 2 and Middle East respiratory syndrome coronavirus

September 9, 2020December 30, 2020 agmcarthur

Arinjay Banerjee, Andrew C Doxey, Benjamin J-M Tremblay, Michael J Mansfield, Sonu Subudhi, Jeremy A Hirota, Matthew S Miller, Andrew G McArthur, Samira Mubareka, &

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antibiotic resistance publications

Overcoming acquired and native macrolide resistance with bicarbonate

September 8, 2020December 30, 2020 agmcarthur

Maya A Farha, Craig MacNair, Lindsey A Carfrae, Sara S El Zahed, Michael Joseph Ellis, Hiu-Ki R Tran, Andrew McArthur, & Eric D Brown ACS

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bioinformatics COVID19 epidemiology genomics molecular epidemiology publications SARS-CoV-2 software virus epidemiology

A Comparison of Whole Genome Sequencing of SARS-CoV-2 Using Amplicon-Based Sequencing, Random Hexamers, and Bait Capture

August 18, 2020December 30, 2020 agmcarthur

Jalees A. Nasir, Robert A. Kozak, Patryk Aftanas, Amogelang R. Raphenya, Kendrick M. Smith, Finlay Maguire, Hassaan Maan, Muhannad Alruwaili, Arinjay Banerjee, Hamza Mbareche, Brian

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COVID19 epidemiology publications SARS-CoV-2 virus epidemiology

Preprint: The PHA4GE SARS-CoV-2 Contextual Data Specification for Open Genomic Epidemiology

August 8, 2020December 30, 2020 agmcarthur

Emma J. Griffiths, Ruth E. Timme, Andrew J. Page, Nabil-Fareed Alikhan, Dan Fornika, Finlay Maguire, Catarina Inês Mendes, Simon H. Tausch, Allison Black, Thomas R.

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genomics publications virus epidemiology

The origins and genomic diversity of American Civil War Era smallpox vaccine strains

July 20, 2020December 30, 2020 agmcarthur

Ana T Duggan, Jennifer Klunk, Ashleigh F Porter, Anna N Dhody, Robert Hicks, Geoffrey L Smith, Margaret Humphreys, Andrea M McCollum, Whitni B Davidson, Kimberly

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COVID19 molecular epidemiology publications SARS-CoV-2 virulence virus epidemiology

Preprint: Early temporal dynamics of cellular responses to SARS-CoV-2

June 30, 2020December 30, 2020 agmcarthur

Arinjay Banerjee, Patrick Budylowski, Daniel Richard, Hassaan Maan, Jennifer A. Aguiar, Nader El-Sayes, Michael R. D’Agostino, Benjamin J.-M. Tremblay, Sam Afkhami, Mehran Karimzadeh, Lily Yip,

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big data COVID19 genomics molecular epidemiology publications SARS-CoV-2 virus epidemiology

Genotyping SARS-CoV-2 through an interactive web application

June 14, 2020December 30, 2020 agmcarthur

Maan, H., H. Mbareche, A.R. Raphenya, A. Banerjee, J.A. Nasir, R.A. Kozak, N. Knox, S. Mubareka, A.G. McArthur, & B. Wang. The Lancet Digital Health,

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bioinformatics genomics publications

Strandedness during cDNA synthesis, the stranded parameter in Htseq-Count and analysis of RNA-Seq aata

May 19, 2020December 30, 2020 agmcarthur

Krishna A Srinivasan, Suman K Virdee, Andrew G McArthur Brief Funct Genomics 2020 May 16 [Epub ahead of print] RNA sequencing (RNA-Seq) is a complicated

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antibiotic resistance databases publications

Detection of Antimicrobial Resistance Using Proteomics and the Comprehensive Antibiotic Resistance Database: a Case Study

December 26, 2019December 30, 2020 agmcarthur

Chen CY, Clark CG, Langner S, Boyd DA, Bharat A, McCorrister SJ, McArthur AG, Graham MR, Westmacott GR, Van Domselaar G Proteomics Clin Appl. 2019

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publications

Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss

December 10, 2019December 30, 2020 agmcarthur

Day EA, Ford RJ, Smith BK, Mohammadi-Shemirani P, Morrow MR, Gutgesell RM, Lu R, Raphenya AR, Kabiri M, McArthur AG, McInnes N, Hess S, Paré

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molecular epidemiology phylogenetics publications

An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp

November 6, 2019December 30, 2020 agmcarthur

Ahmad S, Wang B, Walker MD, Tran H-KR, Stogios PJ, Savchenko A, Grant RA, McArthur AG, Laub MT, Whitney JC Nature 2019 Nov 6. [Epub

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antibiotic resistance big data bioinformatics databases epidemiology genomics molecular epidemiology ontologies publications

CARD 2020: antibiotic resistome surveillance with the Comprehensive Antibiotic Resistance Database

October 30, 2019December 30, 2020 agmcarthur

Alcock BP, Raphenya AR, Lau TTY, Tsang KK, Bouchard M, Edalatmand A, Huynh W, Nguyen A-LV, Cheng AA, Liu S, Min SY, Miroshnichenko A, Tran

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