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Michael G. DeGroote Institute for Infectious Disease Research, McMaster University

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bioinformatics genomics lab members

Welcome Colin Bruce!

June 12, 2023June 16, 2023 agmcarthur

Colin Bruce joins us by way of the laboratory of Dr. Jennifer Stearns and will be completing the last year of his PhD studies with

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Happy 10th Anniversary CARD!

June 11, 2023June 12, 2023 agmcarthur

Today the Comprehensive Antibiotic Resistance Database turns 10 years old! While it started a few years before this in the laboratory of Dr. Gerry Wright,

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antibiotic resistance bioinformatics databases genomics molecular epidemiology software

Chan Zuckerberg ID and the Comprehensive Antibiotic Resistance Database collaborate to add Resistome prediction to the CZ ID platform

May 25, 2023May 25, 2023 agmcarthur

CARD and CZ ID are thrilled to launch a new CZ ID module that allows researchers to detect and analyze antimicrobial resistance (AMR) genes in

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bioinformatics COVID19 genomics SARS-CoV-2 software virus epidemiology

SARS-CoV-2 Illumina GeNome Assembly Line (SIGNAL) update

May 25, 2023May 25, 2023 agmcarthur

The SARS-CoV-2 Illumina GeNome Assembly Line (SIGNAL) has been updated to version 1.6.2, with an important hotfix to address software version incompatibility for rules using

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CBW & VTEC 2023

April 18, 2023May 6, 2023 agmcarthur

They’re back! Thanks to Karyn Mukiri, Jalees Nasir, and Madeline McCarthy for serving as Teaching Assistants for the re-booted Canadian Bioinformatics Workshop in Infectious Disease

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Congratulations Ph.D. student Jalees Nasir!

February 24, 2023February 24, 2023 agmcarthur

Congratulations Jalees Nasir on being awarded the Dr. Jordon Page Harshman Bursary! The Dr. Jordan Page Harsham Bursary was established in 2011 by the Harshman

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antibiotic resistance bioinformatics databases genomics lab members

Team Meta-Model Volunteers

January 10, 2023January 10, 2023 agmcarthur

The McArthur Lab welcomes Team Meta-Model, a volunteer curation team led by former BioPharm Co-Op Keaton Smith, working on curating and upgrading the Comprehensive Antibiotic

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IIDR Trainee Day 2022!

November 16, 2022December 9, 2022 agmcarthur

KARYN MUKIRI – Predicting the total resistome KEATON SMITH – Advancements in curation of the Comprehensive Antibiotic Resistance Database JALEES NASIR – Viral fishing expedition:

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antibiotic resistance bioinformatics databases genomics ontologies publications

CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database

October 20, 2022 agmcarthur

Alcock et al. 2023. Nucleic Acids Res Oct 20, 2022:gkac920. (online ahead of print) The Comprehensive Antibiotic Resistance Database (CARD; card.mcmaster.ca) combines the Antibiotic Resistance

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antibiotic resistance bioinformatics genomics software

Resistome Gene Identifier (RGI) version 6.0.0

September 12, 2022May 25, 2023 agmcarthur

RGI version 6.0.0 – Major release, with parameter and reference data loading changes that may impact scripts. Please see updated README. Added an option (–keep)

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antibiotic resistance bioinformatics genomics lab members

Welcome new M.Sc. student Mateusz Wlodarski!

September 8, 2022October 4, 2022 agmcarthur

The McArthur lab welcomes back past undergraduate student and now newly minted Biochemistry & Biomedical Sciences M.Sc. student Mateusz Wlodarski! Mateusz will be working on

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antibiotic resistance big data bioinformatics genomics publications

Datasets for benchmarking antimicrobial resistance genes in bacterial metagenomic and whole genome sequencing

June 15, 2022June 15, 2022 agmcarthur

Raphenya et al. Scientific Data volume 9, Article number: 341 (2022). Whole genome sequencing (WGS) is a key tool in identifying and characterising disease-associated bacteria

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antibiotic resistance bioinformatics genomics publications

Performance characteristics of next-generation sequencing for the detection of antimicrobial resistance determinants in Escherichia coli genomes and metagenomes

June 1, 2022June 2, 2022 agmcarthur

Rooney et al. 2022 Jun 1;e0002222. Short-read sequencing can provide detection of multiple genomic determinants of antimicrobial resistance from single bacterial genomes and metagenomic samples.

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antibiotic resistance bioinformatics databases genomics molecular epidemiology publications software

Enabling genomic island prediction and comparison in multiple genomes to investigate bacterial evolution and outbreaks

May 19, 2022 agmcarthur

Bertelli et al. Microb Genom. 2022 May;8(5). doi: 10.1099/mgen.0.000818. Outbreaks of virulent and/or drug-resistant bacteria have a significant impact on human health and major economic

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antibiotic resistance big data bioinformatics genomics publications software

Exploring the mobilome and resistome of Enterococcus faecium in a One Health context across two continents

April 13, 2022 agmcarthur

Sanderson et al. 2022. bioRxiv 10.1101/2022.04.11.487771. Enterococcus faecium is a ubiquitous opportunistic pathogen that is exhibiting increasing levels of antimicrobial resistance (AMR). Many of the

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Biochemistry & Biomedical Sciences Research Symposium (BBSRS) 2022!

March 2, 2022March 2, 2022 agmcarthur

Karyn Mukiri – Predicting the Total Resistome Mugdha Dave – Creation and standardization of automated bacterial pathogen genomic sequencing reporting through informatics

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antibiotic resistance bioinformatics genomics IIDR lab members molecular epidemiology

Welcome Madeline McCarthy!

January 4, 2022 agmcarthur

The McArthur lab welcomes Madeline McCarthy, a recent MSc graduate of VIDO / USask, as she join us for her PhD studies in the McMaster

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Jalees Nasir awarded 2021 Fred & Helen Knight Enrichment Award!

July 14, 2021July 14, 2021 agmcarthur

Congratulations to PhD student Jalees Nasir, who has been awarded the prestigious 2021 Fred & Helen Knight Enrichment Award, which recognizes exceptional promise in early

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antibiotic resistance bioinformatics genomics lab members presentations

Summer Conferences 2021

July 5, 2021July 5, 2021 agmcarthur

All online this year due to COVID-19, but some great presentations and virtual posters by our trainees and collaborators! Edalatmand, A. & A.G. McArthur. 2021.

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antibiotic resistance bioinformatics genomics publications

Performance characteristics of next-generation sequencing for antimicrobial resistance gene detection in genomes and metagenomes

June 29, 2021June 29, 2021 agmcarthur

Ashley M. Rooney, Amogelang R. Raphenya, Roberto G. Melano, Christine Seah, Noelle R. Yee, Derek R. MacFadden, Andrew G. McArthur, Pierre H.H. Schneeberger, Bryan Coburn.

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