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Michael G. DeGroote Institute for Infectious Disease Research, McMaster University

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bioinformatics ecotoxicogenomics P450 phylogenetics publications

The cytochrome P450 (CYP) superfamily in cnidarians

May 11, 2021 agmcarthur

Pankov, K.V., A.G. McArthur, D.A. Gold, D.R. Nelson, J.V. Goldstone, J.Y. Wilson. Scientific Reports. 2021 May 10;11(1):9834. The cytochrome P450 (CYP) superfamily is a diverse

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bioinformatics COVID19 epidemiology genomics molecular epidemiology SARS-CoV-2 virus epidemiology

Genomic Epidemiology of SARS-CoV-2: Canada & Ontario

January 15, 2021January 15, 2021 agmcarthur

In collaboration with our colleague Dr. Finlay MaguireĀ (Dalhousie University) and as part of our ongoing work forĀ Ontario’s COVID-19 Genomics Rapid Response Coalition and the Canadian

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bioinformatics genomics IIDR lab members news

Amos Raphenya, MSc Student

January 14, 2021 agmcarthur

It is with great pleasure the McArthur lab announces that Lead Developer for the Comprehensive Antibiotic Resistance Database (CARD), Amos Raphenya, is starting his M.Sc.

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bioinformatics genomics molecular epidemiology publications virulence

Whole genome sequence of Corynebacterium kroppenstedtii isolated from a case of recurrent granulomatous mastitis

December 29, 2020February 7, 2021 agmcarthur

Charlie Tan, Fang-I Lu, Patryk Aftanas, Kara Tsang, Samira Mubareka, Adrienne Chan, & Robert Kozak IDCases. 2020. 23:e01034. We describe the case of a 33-year-old

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bioinformatics genomics publications virulence

Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones

December 16, 2020December 30, 2020 agmcarthur

Shehryar Ahmad, Kara L Tsang, Kartik Sachar, Dennis Quentin, Tahmid M Tashin, Nathan P Bullen, Stefan Raunser, Andrew G McArthur, Gerd Prehna, & John C

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antibiotic resistance bioinformatics databases genomics lab members ontologies presentations

ASMNGS 2020 Virtual Conference – 4th ASM Conference on Rapid Applied Microbial Next-Generation Sequencing and Bioinformatic Pipelines

December 10, 2020December 30, 2020 agmcarthur

Aaron Petkau performed his Visual & Automated Disease Analytics Program internship (Univ. of Manitoba) with us during the summer of 2020, creating the CARD:Live graphic

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antibiotic resistance bioinformatics COVID19 databases epidemiology genomics IIDR lab members molecular epidemiology presentations SARS-CoV-2 text mining virus epidemiology

IIDR Trainee Day 2020! Forging the Future of Infectious Disease Research

November 11, 2020December 30, 2020 agmcarthur

Nasir, J.A et al. 2020. SIGNALing the Need for Surveillance: A Comparison of Whole Genome Sequencing Methods for SARS-CoV-2. Edalatmand, A. & A.G. McArthur. 2020.

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big data bioinformatics COVID19 epidemiology genomics IIDR molecular epidemiology news SARS-CoV-2 virus epidemiology

McArthur Lab & McMaster contribute to global genomic surveillance of SARS-CoV-2

October 21, 2020December 30, 2020 agmcarthur

 

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bioinformatics COVID19 epidemiology genomics molecular epidemiology publications SARS-CoV-2 software virus epidemiology

A Comparison of Whole Genome Sequencing of SARS-CoV-2 Using Amplicon-Based Sequencing, Random Hexamers, and Bait Capture

August 18, 2020December 30, 2020 agmcarthur

Jalees A. Nasir, Robert A. Kozak, Patryk Aftanas, Amogelang R. Raphenya, Kendrick M. Smith, Finlay Maguire, Hassaan Maan, Muhannad Alruwaili, Arinjay Banerjee, Hamza Mbareche, Brian

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bioinformatics COVID19 genomics SARS-CoV-2 virus epidemiology

SARS-CoV-2 Illumina GeNome Assembly Line (SIGNAL)

May 29, 2020December 30, 2020 agmcarthur

Thanks to hard work by Jalees Nasir, Amos Raphenya, Dr. Kendrick Smith (Perimeter Institute), and Dr. Finlay Maguire (Dalhousie) with help from our Ontario Coronavirus

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bioinformatics genomics publications

Strandedness during cDNA synthesis, the stranded parameter in Htseq-Count and analysis of RNA-Seq aata

May 19, 2020December 30, 2020 agmcarthur

Krishna A Srinivasan, Suman K Virdee, Andrew G McArthur Brief Funct Genomics 2020 May 16 [Epub ahead of print] RNA sequencing (RNA-Seq) is a complicated

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antibiotic resistance bioinformatics databases genomics IIDR lab members molecular epidemiology ontologies

New CARD Team Member!

May 2, 2020December 30, 2020 agmcarthur

The McArthur lab welcomes new Curator-Developer William Huynh to the Comprehensive Antibiotic Resistance Database staff. Looking forward to pushing CARD forward with William’s help!

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antibiotic resistance bioinformatics genomics lab members

Summer students!

May 2, 2020December 30, 2020 agmcarthur

The McArthur lab welcomes back summer students Rachel Tran & Arman Edalatmand plus first timers Marcel Jansen & Emily Panousis! These four will be covering

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antibiotic resistance bioinformatics databases genomics IIDR lab members molecular epidemiology ontologies

Congratulations finishing thesis students!

April 6, 2020December 30, 2020 agmcarthur

COVID19 kept us from celebrating together, but we are very proud of the work you have accomplished! Rachel Tran | Biochem 4T15 – Exploring the

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antibiotic resistance big data bioinformatics databases epidemiology genomics molecular epidemiology ontologies publications

CARD 2020: antibiotic resistome surveillance with the Comprehensive Antibiotic Resistance Database

October 30, 2019December 30, 2020 agmcarthur

Alcock BP, Raphenya AR, Lau TTY, Tsang KK, Bouchard M, Edalatmand A, Huynh W, Nguyen A-LV, Cheng AA, Liu S, Min SY, Miroshnichenko A, Tran

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antibiotic resistance big data bioinformatics genomics IIDR publications

Phylogenetic reconciliation reveals the natural history of glycopeptide antibiotic biosynthesis and resistance

August 19, 2019December 30, 2020 agmcarthur

Waglechner N, McArthur AG, Wright GD. Nat Microbiol. 2019 Aug 12. [Epub ahead of print] Glycopeptide antibiotics are produced by Actinobacteria through biosynthetic gene clusters

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antibiotic resistance big data bioinformatics databases genomics lab members molecular epidemiology outreach presentations

MacData Summer School 2019

May 31, 2019December 30, 2020 agmcarthur

Dr. McArthur and PhD student Kara Tsang taught together at the 2019 MacData Institute Summer School, with Dr. McArthur reviewing biocuration and bioinformatics for genomic

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antibiotic resistance bioinformatics genomics molecular epidemiology software

RGI 5 Released!

March 26, 2019December 30, 2020 agmcarthur

April 2019 big #card_release #RGI5! Resistance Gene Identifier Version 5: entirely new algorithms for metagenomics data, new options for genomes & assemblies. Extensively updated documentation,

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antibiotic resistance bioinformatics databases genomes molecular epidemiology ontologies

Recent Updates to the Comprehensive Antibiotic Resistance Database

March 19, 2019December 30, 2020 agmcarthur

The Comprehensive Antibiotic Resistance Database has been updated, http://card.mcmaster.ca CARD Curation: Expanded MCR, OXA & IMP beta-lactamase, and macrolide phosphotransferase (MPH) sequence curation. Updated nomenclature

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antibiotic resistance bioinformatics databases genomics IIDR molecular epidemiology ontologies presentations software teaching

State of the CARD 2019

January 31, 2019December 30, 2020 agmcarthur

A week of lectures, demos, and training for the Comprehensive Antibiotic Resistance Database During McMaster Spring Mid-Term Recess (February 18-24), the McArthur lab is pleased

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